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KMID : 1007520160250000103
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Food Science and Biotechnology
2016 Volume.25 No. 0 p.103 ~ p.106
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Protective Effect of Resveratrol against Pseudorabies Virus-induced Reproductive Failure in a Mouse Model
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Su Dingding
Wu Shusong
Guo Jing
Wu Xiaosong
Yang Qing
Xiong Xingyao
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Abstract
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Resveratrol (RES), a natural polyphenol that is abundant in grapes, exerts anti-inflammatory, anti-oxidative, and antiviral bioactive effects. Protective effects of RES against pseudorabies virus (PrV)- induced reproductive failure were investigated in a mice model. Injection of PrV partially induced stillbirth and abortion, and caused poor growth of progeny. Treatment with RES attenuated the reproductive failure induced by the virus with recovery of the serum progesterone level. RES improved the growth performance of newborn mice. RES can attenuate the reproductive failure induced by PrV in mice.
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KEYWORD
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resveratrol, antivirus, pseudorabies, reproductive failure
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